Chromatography tests the radiochemical purity of specific
radiopharmaceuticals. The accompanying chart shows
which strips and solvents are required to perform each individual test.
Some solvents must be purchased separately (see SigmaAldrich
due to hazardous material shipping restrictions.
Detailed instruction manuals are packaged with each strip container, although our Radiopharmaceutical QC Procedure Manual (151000) explains paper chromatography in greater detail.
Tec-Control Aluminum Breakthru Kit
The Aluminum Break¬thru Kit provides a rapid, easy and inexpensive way to test aqueous solutions, particularly per¬tech¬netate generator eluate, for trace quantities of alu¬minum. Aluminum forms an intense red precipitate with the indicator paper, and the intensity of the color is directly proportional to the amount of aluminum in the solution. The USP allows a concentration of aluminum ion in an injection 10 micrograms per milliliter (10 μg/ml) in technetium 99m eluate prepared from Molybdenum 99 formed as a result of uranium fission.
Simple Procedure: Place a drop of the eluate or solution to be tested on the indicator paper. The best procedure is to form a hanging drop using a 1922G needle. Place a drop of the standard aluminum solution on the indicator paper. Use the same size drop. Compare the intensity of the red spot formed. If the eluate spot is less intense than the standard solution, the eluate contains less than 10μg/ml aluminum.
Radiopharmaceutical QC Manual
This detailed manual explains Paper Chromatography, a QC method for evaluating the radiochemical purity of currently used Tc99mlabeled radiopharmaceuticals. Procedures are quick and easy to use, a simple quality control solution for any nuclear medicine department.